$\begin{align} P(U, V, W, X, Y) &= P(U)P(V|U)P(W|U, V)P(X|W, U, V)P(Y|W, U, V, X) \\ &= P(V)P(U|V)P(W|U, V)P(X| W, U, V)P(Y| W, U, V, X) \\ &= P (V)P(U|V)P(W|U, V)P(Y| W, U, V)P(X| W, U, V, Y) \\ &= P(U)P(V| U)P(W|U, V)P(Y| W, U, V)P(X| W, U, V, Y) \\ &= P(U)P(V)P(W|U, V)P(X| W)P(Y| W) \end{align}$
From above we can see,
A. $P(Y|W, U, V) = P(Y| W) \implies$ Y is conditionally independent of V given W. Option A can beTrue.
B. $P(X|W, U, V) = P(X| W) \implies$ X is conditionally independent of U given W. Option B can be True.
C.$P(U|V) = P(U), P(V|U) = P(V) \implies$ U and V are independent. But from this we can't say whether option C is either True or False.
D. From A and B, we can say this can be also True.
Answer - C